Curriculum Vitae

Dr. Ali Mohammad Ahadi

PhD in Molecular Genetic 

Personal Information
	Born:	July 22, 1973, Kashan, Iran
	Present address:	P.O. Box: 115- Department of Genetics – School of science- Shahrekord University-Shahrekord- Iran
	Mobile /Telephone:	03814424406
	E-mail:	ahadi_al@sci.sku.ac.ir
	Alternative Emai:	ahadi_al@yahoo.com

Occupation
	Assistant Professor In Molecular Genetic in Shahrekord University. Manager of Genetic Department in Shahrekord University.

Education
	2006:	Ph. D. in molecular genetics, University of Tarbiat Modarress, Faculty of  Science, Department of Genetics and National Research Center of Genetic Engineering and Biotechnology (NRCGEB) . Thesis: study of genetic alterations in epileptic disorders. Advisor: Dr. Majid Sadeghizadeh
	2001:	M.Sc in Genetics, University of Tarbiat Modarress, Science faculty, Department of Genetics. Thesis: Genetic diversity in Iranian ethnic groups. Advisor: Dr. S. Kazem Bidooki
	1997:	Bs.c in Biology, University of Isfahan, Science faculty, Department of Zoology.

Languages
	Persian English

Awards
	1997	Isfahan University Award for top undergraduate students
	2005	First Epilepsy in IRAN Congress Award

Honors
	1997	Top student in B.Sc. (grade 1)
	1999	Number six candidate in genetic in national M.sc. exam
	1999	Number one candidate in Medical Biochemistry M.sc. exam .
	2001	Number one candidate in Molecular genetic PhD exam.

Teaching Experience
	1999 – 2006	Medical genetics (MD course),Molecular genetic (MSc. Of medical microbiology)  Medical Science Kashan University.
	2002 -2006	Molecular Genetics and Medical genetics, B.Sc. students. Shahed University .
	2005-present	Molecular and Medical Genetics, cytogenetic , Genetic engineering,     Developmental and evolutional genetics  B.Sc. and MSc. Students.      Shahrekord University.

	Technical Experience
		PCR Based Methods(SSCP, DGGE, RFLP,ARMS, RAPD, AFLP,STR, SSR, VNTR, MNC-PCR, HLA-Typing and ……) Sequencing Based Diagnostic Methods. Molecular cloning methods
	Membership and collaboration in scientific Associations
	1.      Iran Medical Genetic Associations 2.      Iran Epilepsy Associations 3.      Iran Neurogenetic Associations 4.      Iran Biology Associations 5.      A member of Founder Board of Iran Genetic Counseling Association 6.      Shahrekord university Biotechnology committee

Research Experience

Accomplished and Ongoing Researches :
	1. Cloning and expression of timp-4 in prokaryotic system. 2. Cloning and expression of fusion proteins in prokaryotic system. 3. Protein engineering by site directed mutagenesis. 4. Recombinant viral Vaccines. 5. Study of Genetic diversity in Iranian ethnic groups by PCR-RFLP method. 6. Design and development of new strategies in DNA Extraction from different cell and tissues. 7. Study of genetic alteration in some type of epileptic disorder in IRAN. 8. Study of mutation in GABRG2 gene in the patients affected by Generalized Epilepsy with Febrile Seizures Plus (GEFS+) and Severe Myoclonic Epilepsy of Infancy (SMEI) using PCR-SSCP method. 9. Study of SCN1A mutation in Severe myoclonic epilepsy  of infancy(SMEL) and Generalized epilepsy with febrile seizures plus (GEFS+) by PCR-SSCP in Chaharmahal Va Bakhtiari province. 10. Study of genetic alteration in cystatinB gene In EPM1. 11. Organization of a genome bank containing of genomic DNA from Idiopathic Epileptic patients. 12. Preimplantation gender determination of  human embryos by single cell PCR method. 13. Comparative study of genes expression in early stages of embryo development 14. Leishmania Typing By using of PCR Based Method. 15. Design and Optimization of a molecular based diagnostic method for detection and typing of Brucella.   16. Study of genetic diversity in some type of Iranian horse breeds.

As Supervisor in MS.c. Thesis:
1	Farnaz Farzaneh, Gender determination in single bovine blastomeres by multiplex nested single cell polymerase chain reaction. Islamic Azad University, Science and Research Unit. Graduated
2	Sulmaz Khademi, Study of etiological role of ion channels in patients affected by Idiopathic Generalized Epilepsy (IGE).Shahrekord University. Graduated
3	Atefeh Sharifi-rad, Cloning and expression of functional domains of timp-4 gene in prokaryotic system. Shahrekord University. Graduated
4	Mohammad Taghdiri; Shahrekord University. Decedent!!
5	Hajar Yaghubi, Study of mutation in GABRG2 gene in the patients affected by Generalized Epilepsy with Febrile Seizures Plus (GEFS+) and Severe Myoclonic Epilepsy of Infancy (SMEI) using PCR-SSCP method. Islamic Azad University, Science and Research Unit. Graduated.
6	Zeynab Amini, Study of genetic alteration in cystatinB gene In EPM1. Azad University, Science and Research Unit. Graduated
7	Amin Izaditabar. The effect of Gabapentin and Clonazepam treatment in induction of mdr1a gene expression in animal model.Shahrekord University,
8	Somayeh khatami, , Sequencing and study of promoter region of ETF3 gene in vertebrates and its association with early abortion and expression analyses of it in embryonic cells cocultured with Mesenshimal stem cells. Shahrekord University

As advisor in MS.c. and Vetinary Science Thesis:
1	Rahim Barzegar. Study of genetic diversity in some type of Iranian gourd variants by using of biochemical, molecular and morphological traits. Gylan University. PhD student In Horticulture.
2	Camellia Taghadosi. Detection of bovine leukemia viruse by PCR and RT-PCR in tumor tissue of human with lymphoma and lymphosarcoma. Shahrekord University, Graduated
3	Nilofar Taghizadeh, Identification of leyshmania isolates from patient with dermal injuries by PCR method. Shahrekord University, Graduated.
4	Samaneh jahanabadi. Effect of selenium nanoparticles on Iron homeostasis and transferin receptor gene expression.  Shahrekord University, Graduated.
5	Samira Asgharzadeh. Study of effect of media composition on rate of differentiation of mesenshymal stem cell to osteocyte. Shahrekord University, Graduated.
6	Afsaneh safdari. Effect of duration of maturation of bovine oocytes on the sex ratio of produced bovine embryo. Shahrekord University, Graduated.
7	Sorena firuzi. Primitive molecular and comparative studies among samples from some ancient ethnic and modern Iranian people groups. Shahrekord University, Graduated.
8	Parvin zamani. A new view to conservation of stony lion open air of historical cemeteries. Isfahan Art University, Graduated.
9	Ahura nozari study of polymorphism in TNFα and IL1Ra Genes with predisposition in infant affected by Febrile seizure. Chamran Univeristy, Graduated.
10	Sheyda Ilkhanizadeh, Sequencing and cloning of Iranian scorpion “Mesobuthus” cholorotoxin in prokaryotic system Shahrekord University, Graduated.
11	Elham Asadi, Comparative study of IGF-1 and OCT4 genes expression in early stages of embryo development by using of Semi Quantitative-RT-PCR method, Shahrekord University, Graduated.
12	Mohammad zebarjad, the impact of some environmental agents on coelomic fluids protein profile in red earth worm (Lumbricus rubellus) . Shahrekord University, Graduated.
13	Peyman Faramarzi, Analysis of oral consumption of selenium nanoparticles on Hsp gene expression after a hard practices. shahrekord University.

Publications

1.      Tafreshi NK, Sadeghizadeh M, Amini-Bavil-Olyaee S, Ahadi AM, Jahanzad I, Roostaee MH.Development of a multiplex nested consensus PCR for detection and identification of major human herpesviruses in CNS infections. J Clin Virol. (2005)32(4):318-24.

2.      Ali-Mohammad Ahadi, Majid Sadeghizadeh, Koorosh Gharagozli and Massoud Houshmand. Confirmation of R82Q Mutation in g2 Subunit of Gamma Amino Butyric Acid Receptor in an Iranian Family  .Pakistan Journal of Biological Sciences 9 (14): 2704-2707, 2006

3.      Jahanzad I, Sadrzadehrafie AH., Rafie R., Rahmanian M., Hayeri MR., Rezaee AR., Gharaei B., Sadeghizadeh M., Ahadi AM., Is There any Correlation between Ki67 Expression and EBV Infection in Hodgkin Patients in Iran. Iranian Journal of Pathology (2007)2 (1), 17-22

4.      Khalaj-Kondori M., Sadeghizadeh M., Khajeh K., Naderi-Manesh H., Ahadi AM., Emamzadeh A., Cloning, Sequence Analysis and Three-dimensional Structure Prediction of DNA Pol I from Thermophilic Geobacillus sp. MKK Isolated from an Iranian Hot Spring. Applied Biophysics and biochemistry,2007(142):200-208.

5.      Ahadi AM., Sadeghizadeh M., Houshmand M., Gharagoozli K., Banoei MM., Shafa M., An A8296G mutation in the MT-TK gene of a patient with epilepsy – a disease-causing mutation or rare polymorphism? Neurologia i Neurochirurgia Polska 2008; 42, 3: 263–266.

6.      Farnaz Farzaneh.Dehkordi, Ali Mohammad Ahadi, Abolfazl Shirazi, Majid Sadeghizade. Effect of lysis strategy in accuracy and repeatability of sex determination by single cell Polymerase Chain Reaction method. J. Of Biological Science 2009;9(1):78-82,

7.      Ali Mohammad Ahadi , Farnaz Farzaneh Dehkordi, Abolfazl Shirazi, Hasan Nazari, Ebrahim Ahmadi, Hoda Ayat, Majid Sadeghizadeh. Gender determination in single bovine blastomeres by multiplex nested single cell polymerase chain reaction(MNSC-PCR). J. Iran. Chem. Soc., Vol. 6, Suppl., November 2009, pp. S103-S114

8.      Nozari A., Forooghmand AM., Ahadi AM., Khoshdel A., Hahemzadeh Chaleshtori M., Association study between IL1RA gene polymorphism with febrile convulsion in Shahrekord children. Journal of Shahrekord University of Medical Sciences. 2010;12 (3):29-36.

9.    Khademi S., Ahadi AM., Mehvari J., Ayat H., Farrokhi E., Moradi MT., Hashemzadeh Chaleshtori M., Detection of A1430G mutation in SCN1A gene in a patient affected by GEFS-Like Epilepsy in Chaharmahal and Bakhtiari Province. Journal of Shahrekord University of Medical Sciences. Accepted.2011.

10.  Ilkhani zade S, Ayat H., Ahadi AM., Pirali K., Sequencing and Comparative-Bioinformatic Analysis of Chlorotoxin-Like Peptide from the Iranian Scorpion Mesobuthus eupeus. J Journal of Shahrekord University of Medical Sciences. Accepted.2011.

Conferences
	2001	Ahadi A.M. and Bidooki K.,Genetic biodiversity in Iranian ethnic groups . 6th  national biochemistry annual meeting:, Iran University. Tehran.
	2005	Ahadi A.M. , Sadeghizadeh M., Gharagoozli K., Study of genetic alterations in sodium ion channels in epileptic disorders. First national epilepsy annual meeting, Imam Khomeini Hospital, Tehran,
	2005	Ahadi A.M. , Sadeghizadeh M., Gharagoozli K., study of genetic alteration in SCN1A, SCN1B and GABRG2 gene in the patient with epileptic disorders.14th national and 2nd international   confereance of biology. Tarbiat modares University, Tehran,
	2006	Miri M., Ahadi AM., Jahanian L., Diagnosis of unfeigned conserved tuna fish. 2nd international conference of food industry.. Industry Isfahan University, Isfahan.
	2006	Ahadi A.M. Epilepsy and genetics. 7th conference on epilepsy. Invited lecturer. Mofid Hospital, Tehran.
	2006	Ahadi A.M. , Sadeghizadeh M., Gharagoozli K., Houshman M., An A8296G mutation in mitochondrial tRNA Lys gene: many phenotypes caused by  similar genotype!!, June 1, NHS:. Milan, Italy.
	2009	Solmaz Khademi, Ali Mohammad Ahadi, Morteza Hashemzadeh Chaleshtori,Jafar Mehvari, Hoda Ayat, Effat Farrokhi. Study of etiological role of ion channels in patients affected by Idiopathic Generalized Epilepsy (IGE) in Chahar Mahal va Bakhtiyari Province.first National conference of biology Student. Shahrekord university. Shahrekord.
	2009	Setareh Banitalebi, Fattaneh Keyvani, Ali Mohammad Ahadi. Mechanisms involved in rejection of paternal mitochondria in early stages of post-fertilization. first National conference of biology Student. Shahrekord university. Shahrekord.
	2009	Reihaneh Farghadani, Solmaz Khademi, Ali Mohammad Ahadi, Hoda Ayat, Mehran Arabi. The homology study of some Hox family genes between invertebrates and human. first National conference of biology Student. Shahrekord university. Shahrekord.
	2009	Sharifirad A., Ahadi A M., Ayat H., Shirazi A., Ahmadi E., Nazari H. Analysis of homology between otx2 sequences of Iranian sheep and other close related species.first National conference of biology Student. Shahrekord university. Shahrekord.
	2009	Ahadi A M., Ayat H., Self citation and Plagiarism.first National conference of scientific development and revolution year. Shahrekord university. Shahrekord.
	2009	Asadi E., Ahadi A.M, Shirazi A., Ahmadi E. , Nazari H.The study of gene markers polymorphism in various races of Iranian sheep. first National conference of biology Student. Shahrekord university.Shahrekord.
	2009	Ilkhanizadeh Sh., Ayat H., Ahadi A M., Sharifirad A., Pirali K., Analysis of probable prediction of Arachnoid toxins motives contributing to interaction with ion channels. first National conference of biology Student. Shahrekord university. Shahrekord.
	2009	Ali Mohammad Ahadi, Abolfazl Shirazi, Farnaz Farzaneh Dehkordi, Hasan Nazari, Ebrahim Ahmadi, Majid Sadeghizadeh. Effect of lysis strategy in accuracy and repeatability of sex determination by single cell Polymerase Chain Reaction method. 10th National conference in biochemistry. Tehran, Iran
	2010	Ahadi A.M., Ayat H., Sadeghizadeh M., Gharagoozli K., Houshman M., Solmaz Khademi,  Study of Parental consanguinity and other diagnostic factors in Iranian patients affected with idiopathic generalized epilepsies. 11th Iran congress on Genetics. Shahid Beheshti University. Tehran, Iran.
	2010	Solmaz Khademi, Ali Mohammad Ahadi, Morteza Hashemzadeh Chaleshtori,Jafar Mehvari, Hoda Ayat. A Missence Mutation in α1 subunit of Sodium-Channel Gene (scn1a) in a patient affected by Severe Myoclonic Epilepsy of Infancy. 11th Iran congress on Genetics. Shahid Beheshti University. Tehran,Iran.
	2010	Ali Mohammad Ahadi, Farnaz Farzaneh Dehkordi, Abolfazl Shirazi, Hoda Ayat, Hasan Nazari, Ebrahim Ahmadi, , Majid Sadeghizadeh. Optimization of diagnostic sensitivity of DNA extension in the standard condition of Multiplex PCR and comparison with Nested Multiplex PCR in sex determination of Bovine. 11th Iran congress on Genetics. Shahid Beheshti University. Tehran, Iran
	2010	Momeneh Foroutan, Ramyar Molania, Atefeh Sharifi rad, Dr .Ali Mohamad Ahadi, Dr .Hoda Ayat. A comparative study between amino acid containing and codon usage in otx and oct gene families. 16th National and 4th International Conference of Biology. Ferdowsi University of Mashhad, Mashhad, Iran.
	2010	Sheyda Ilkhani Zadeh, Dr .Hoda Ayat, Dr .Ali Mohammad Ahadi, Dr.Khodadad Pirali. Sequencing and cloning of Iranian scorpion “Mesobuthus” cholorotoxin in prokaryotic system.16th National and 4th International Conference of Biology. Ferdowsi University of Mashhad, Mashhad, Iran
	2010	Atefeh Sharifi-rad, Dr. Ali Mohammad Ahadi, Dr. Hoda Ayat. Cloning and expression of functional domains of timp-4 gene in prokaryotic system. 16th National and 4th International Conference of Biology. Ferdowsi University of Mashhad, Mashhad, Iran.
	2010	Abdolrashid Zebarjad, Mehran Arabi, Ali -mohammad Ahadi. Changes in coelomic fluid protein pattern and antioxidant power in red earthworm (Lumbricus rubellus) following physico-chemical stresses. 16th National and 4th International Conference of Biology. Ferdowsi University of Mashhad, Mashhad, Iran.
	2011	Ahadi A.M., Yaghubi H., Haeri Rohani M., Study of GABRG2 genes mutations involved in the occurrence of GTCS (Grand mal ) epilepsy by using PCR-SSCP method. 11th national congress in biochemistry. Qazvin Medical university.